Patía, Colombia

With a population of just 37,781, Patía is a far cry from the bustling metropolises that draw most expats. The town sits along the 400-kilometer Patía River, which flows westward through cloud forests and dry valleys before emptying into the Pacific. While the last 56 miles are navigable by boat, the region's remote location and mountainous terrain make it a bureaucratic headache to access. Residents must also contend with the Chocó jungles that dominate the lower section of the river. Patía may appeal to the rugged individualist seeking an off-the-grid adventure, but for the average American seeking an easy overseas lifestyle, this isolated corner of Colombia likely does not fit the bill.