Rurópolis, Brazil

The population of Rurópolis is just 19,468, making it a sleepy backwater even by Brazilian standards. While the town sits on the edge of two national forests, that means dealing with the country's notorious bureaucratic headaches over logging and land use. The climate is hot and humid, and crime rates are not well documented - a persistent issue across much of the Amazon region. If you're seeking a remote, rustic lifestyle with access to nature, Rurópolis may appeal. But for most, the isolation and lack of amenities will outweigh any potential upsides.