Oriximiná, Brazil

At just over 41,000 residents, Oriximiná is a remote outpost in the Amazon rainforest, far from the comforts of Brazil's coastal cities. The municipality covers a massive territory, home to vast protected forests and reserves, but this isolation comes at a cost. Bureaucracy is a persistent headache, with residents relying on small regional airports to access the outside world. And while the natural scenery is undoubtedly impressive, the steamy equatorial climate is not for the faint of heart. Oriximiná is best suited for intrepid adventurers and nature lovers willing to embrace the challenges of life in the Amazon.