Eirunepé, Brazil

The population of 20,372 makes Eirunepé one of the largest cities in the Amazon region. However, don't let the size fool you - this remote outpost, over 1,000 kilometers from the state capital, has a persistent bureaucratic headache that can make daily life a challenge. The climate is hot and humid year-round, with temperatures swinging from a low of 8.5°C to a high of nearly 40°C. While the city's airport connects it to the outside world, the journey is long and arduous for most. Eirunepé is best suited for those seeking a true off-the-grid Amazonian experience, far from the comforts of modern Brazil.